Plural Publishing produces leading academic, scientific and clinical publications in the fields of speech-language pathology, audiology, and otolaryngology.


The Larynx, Volume II

Third Edition
Edited by: Marvin P. Fried, Alfio Ferlito
Co-Editors: Alessandra Rinaldo, Richard V. Smith
847 pages, Illustrated (B/W), Hardcover, 8.5 x 11"
Release Date:


This new, landmark edition represents an amalgamation of two of the most famous and well reviewed books on the science, diagnosis, clinical management, and surgical and non-surgical treatment of laryngeal diseases and disorders.

The Larynx 3rd edition merges Ferlito’s Diseases of the Larynx (2000, copublished by Arnold in the UK and OUP in the US) and Fried’s The Larynx: A Multidisciplinary Approach, 2nd Edition (Mosby).

Totally revised, completely updated, and massively expanded, the new edition comprehensively covers the subject area and encompasses the talents of the world-leading international specialists drawn from every conceivable field with an interest in the larynx, among them pediatric and adult laryngologists, voice and speech pathologists, anatomists and physiologists, pathologists, radiologists, anesthesiologists, oncologists, chemotherapists, radiotherapists, and immunologists. The must-have ENT volume in every medical library, laryngologist’s office and speech pathology department library.


  • Neil Weir, Journal of Laryngology and Otology (2009):
    "... The two volumes hold a wealth of information ... This splendid book is an essential reference for all ENT departments’ libraries. ..."

  • Part I. Larynx and Deglutition
    • 1. Disorders of the Upper Esophageal Sphincter
      Keith G. Saxon, Sandra Martin, Raj K. Goyal, Jo Shapiro
    • 2. Gastroesophageal Reflux Disease and Voice Disorder
      James H. Kelly, Kevin P. Lahey
    • 3. Diagnosis and Management of Dysphagia
      Celia F. Stewart, Phillip C. Song, Andrew Blitzer
    • 50. Evaluation and Management of Chronic Aspiration
      Phillip Song, Jerome Schwartz, Andrew Blitzer
  • Part II. Laryngotracheal Trauma
    • 5. Traumatic Disorders of the Pediatric Larynx
      David L. Mandell, Robert F. Yellon
    • 6. Evaluation and Management of Laryngotracheal Trauma
      Simon R.A. Best, John K. Joe, Douglas A. Ross, Clarence T. Sasaki
    • 7. Laryngeal Stenosis
      Indranil Debnath, Randal C. Paniello, J. Gershon Spector
  • Part III. Larynx Endocrine Systems
    • 8. Endocrine Disorders of the Larynx
      Mai Thy Truong, Edward J. Damrose
    • 9. Diseases of the Thyroid as they Affect the Larynx
      Larry J. Shemen
  • Part IV. Benign Laryngeal Lesions
    • 10. Nodules, Polyps, Reinke Edema, Metabolic Deposits, and Foreign Body Granulomas
      Frederik G. Dikkers
    • 11. Laryngeal Cysts, Pseudocysts, and Laryngoceles
      Seth M. Cohen, J. Pieter Noordzij, C. Gaelyn Garrett, Mark S. Courey, Robert H. Ossoff
  • Part V. Neoplasms of the Larynx
    • 12. Benign Neoplasms of the Larynx
      Ramon A. Franco, Jr., Jeffrey N. Myers, Eugene N. Myers, E. Leon Barnes
    • 13. Microlaryngoscopy and Endolaryngeal Microsurgery
      Lucian Sulica
    • 14. Epidemiology and Pathogenesis of Laryngeal Carcinoma
      Cristina Isabel Cann, Marvin P. Fried
    • 15. Experimental Laryngeal Carcinogenesis and Mechanism Studies
      Umberto Saffiotti
    • 16. Specific Immunologic Aspects of Laryngeal Cancer
      William J. Richtsmeier
    • 17. Molecular Biology of Laryngeal Cancer
      Thomas E. Carey, Carol R. Bradford
    • 18. Laryngeal Pathology
      Margaret S. Brandwein-Gensler, Panna Mahadevia, Douglas R. Gnepp
    • 19. The Classification and Staging of Laryngeal Cancer
      Katherine C. Yung, Jay F. Piccirillo, Peter D. Lacy
    • 20. Laryngeal Epithelial Changes: Diagnosis and Therapy
      Alfio Ferlito, Patrick J. Bradley, Alessandra Rinaldo
      21. Cancer of the Supraglottis
    • Alfio Ferlito, Richard V. Smith, Carl E. Silver, Alesandra Rinaldo
    • 22. Surgical Treatment of Supraglottic Cancer
      Carl E. Silver, Alfio Ferlito, Richard V. Smith, Alessandra Rinaldo
    • 23. Cancer of the Glottis
      Richard V. Smith, Marvin P. Fried
    • 24. Conservation Surgery for Glottic Cancer
      Dana M. Hartl, Daniel F. Brasnu, Marvin P. Fried
    • 25. Cancer of the Subglottis
      Bradley A. Schiff, Richard V. Smith
    • 26. Cancer of the Hypopharynx
      Jatin P. Shah, Jennifer M. Bocker
    • 27. Voice Rehabilitation After Total Laryngectomy
      Ranny van Weissenbruch
    • 28. Peristomal Cancer
      Alfio Ferlito, Carl E. Silver, Alessandra Rinaldo
    • 29. Cancer of the Larynx: Treatment of the Neck
      Jesus E. Medina
    • 30. Treatment of the N0 Neck in Nonconventional Neoplasms of the Larynx
      Alfio Ferlito, Alessandra Rinaldo, Kenneth O. Devaney, Vanni Mondin
    • 31. Managing Complications of Surgical Laryngeal Intervention
      Yasushi Murakami, Yasuo Hisa
    • 32. Radiation Therapy for Laryngeal Cancer
      Madhur K. Garg, Shalom Kalnicki
    • 33. Chemotherapy in the Management of Laryngeal Cancer
      Missak Haigentz Jr.
    • 34. The Management of Recurrent Laryngeal Cancer
      Richard V. Smith, Bradley A. Schiff, Marvin P. Fried
    • 35. Prognostic Factors of Laryngeal Cancer
      Alfio Ferlito, Byron J. Bailey, Alessandra Rinaldo
    • 36. Chemoprevention of Laryngeal Cancer
      Boudewijn J.M. Braakhuis, C. René Leemans
    • 37. Secondary Neoplasms of the Larynx
      Adel K. El-Naggar
    • 38. Pregnancy and Cancer of the Larynx
      Alfio Ferlito, Jan Olofsson
    • 39. Paraneoplastic Syndromes in Patients with Cancer of the Larynx and Hypopharynx
      Alfio Ferlito, Alessandra Rinaldo
    • 40. Laryngeal Transplantation
      Robert R. Lorenz, Marshall Strome
    • 41. Psychological Issues in Laryngeal Disease and Laryngeal Surgery
      Frank E. Lucente, James J. Strain, Jared Wasserman, Boris L. Bentsianov
    • 42. Future Directions in Laryngeal Cancer Research and Therapy
      Nicolas F. Sclecht, Thomas J. Belbin, Michael B. Prystowsky, Richard V. Smith
  • Index

About The Editors

Marvin P. Fried

Marvin P. Fried, MD, FACS, completed his residency at Washington University, in St. Louis, and served in the U.S. Public Health Service. He joined the faculty at Boston University, Tufts University, then Harvard Medical School, where he was promoted to professor of otology and laryngology. He later became professor of otolaryngology-head and neck surgery and university chairman at the Albert Einstein College of Medicine and Montefiore Medical Center.

Alfio Ferlito

Alfio Ferlito, MD is Director of the Department of Surgical Sciences, Professor and Chairman of the ENT Clinic at the University of Udine School of Medicine. He graduated in medicine at the University of Bologna. After two years at the University of Trieste, he worked at the ENT Department of Padua University from 1970 to 1997.

He has collaborated in writing articles, editorials, commentaries, letters to the editor, special issues, book chapters and books with 323 international experts.

He has edited a three-volume book entitled Cancer of the Larynx (CRC Press, Boca Raton, 1985) and three other books entitled Neoplasms of the Larynx (Churchill Livingstone, Edinburgh, 1993), Surgical Pathology of Laryngeal Neoplasms (Chapman and Hall, London, 1996) and Diseases of the Larynx (Arnold, London, 2000), and co-authored two books entitled Granulomas and Neoplasms of the Larynx (Churchill Livingstone, Edinburgh, 1988) and Surgery for Cancer of the Larynx and Related Structures together with Dr. Carl E. Silver (Saunders, Philadelphia, 1996). He is editor with Dr. Marvin P. Fried of The Larynx (Plural Publishing). He has been the author or co-author of 383 refereed publications in 46 medical journals and 48 chapters in various books.

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